Martinović Klarić, Irena and Peričić, Marijana and Barać Lauc, Lovorka and Janićijević, Branka and Kubat, Milovan and Pavičić, Dino and Rudan, Igor and Wang, Ning and Jin, Lin and Chakraborty, Ranajit and Deka, Ranjan and Rudan, Pavao (2005) Genetic variation at nine short tandem repeat loci among islanders of the eastern Adriatic coast of Croatia. Human biology, 77 (4). pp. 471-486. ISSN 0018-7143 (Print), 1534-6617 (Online)
Full text not available from this repository. (Request a copy)Abstract
We have analyzed the extent of genetic variation at nine autosomal short tandem repeat loci (D3S1358, vWA, FGA, THO1, TPOX, CSF1PO, D5S818, D13S317, D7S820) in six populations from Croatia, five of which are distributed in the islands of the eastern Adriatic coast and one is from the mainland. The purpose is to investigate the usefulness of these loci in detecting regional level genetic differentiation in the studied populations. Significant heterogeneity among the island and mainland populations is revealed in the distributions of allele frequencies ; however, the absoulute magnitude of the coefficient of gene differentiation is small but significant. The summary measures of genetic variation, viz., heterozygosity, number of alleles and allele size variance, do not indicate reduced genetic variation in the island populations compared to the mainland population. In contrast of the two measures of genetic variation, allele size variance and within locus heterozygosity, the imbalance index (b) indicates evidence of recent expansion of population sizes in all islands as well as in the mainland. High mutation rates of the studied loci, together with local drift effects are likely explanations for inter-island genetic variation and the observed lack of reduced genetic diversity among the island populations.
| Item Type: | Article |
|---|---|
| Additional Information: | Language: English. |
| Uncontrolled Keywords: | Short tandem repeats, genetic variation, D3S1358, VWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317, D7S820, eastern Adriatic islands, Dalmatian islands, Croatia |
| Subjects: | G Geography. Anthropology. Recreation > GN Anthropology R Medicine > RA Public aspects of medicine |
| Depositing User: | Karolina |
| Date Deposited: | 13 Jan 2017 10:21 |
| Last Modified: | 13 Jan 2017 10:36 |
| URI: | http://idiprints.knjiznica.idi.hr/id/eprint/685 |
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